Clinically studied for hormonal acne

Topical Spironolactone 5%

(Anti-androgen cream)

Prescription cream used to treat hormonal acne by reducing oil production and blocking androgens. May help reduce blackheads and inflammatory breakouts.

$43/month, billed quarterly

Get 10% off with code WELCOME10

FDA regulated pharmacy

FSA / HSA payment options

Free shipping

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Real Results in Weeks

Clinical studies show results can be seen in as little as 8 weeks.

“After about 2 months, the painful cystic spots around my jawline started clearing up. It didn’t happen overnight, but it’s been a game-changer for me.”

Haylee K.

“I was nervous to try something new, but this didn’t irritate my skin at all. My blackheads and small bumps are way better now, and I finally feel good going makeup-free. You really have to stick with it and be patient to notice results!”

Jessica P.

Before

After

Before

After

How it works

Blocks androgen receptors in the skin.

This can lower sebum production and help prevent clogged pores.

Results in weeks

Visible acne improvement seen in as few as 8 weeks. 

How Oana works

1. Complete a 5-min online visit

Fill out a brief intake on your medical history and specific health needs.

2. Get medical approval

A licensed medical professional will review your health history to prescribe your treatment.

3. Shipped to your doorstep

All treatments are shipped directly to you with free shipping.

Clinically proven

Clearer skin in 8 weeks
Studies in men and women showed fewer breakouts in just 2 months.

Safe for all skin types

Studies showed that topical spironolactone didn’t significantly affect skin hydration, oil balance, or cause irritation—making it a gentler option for long-term use.

FAQs

What are the side effects?

Topical spironolactone is generally well tolerated. Some people may experience mild redness, dryness, or stinging at the application site. These effects are usually temporary and may go away as your skin adjusts. Contact your healthcare provider if irritation continues.

How does Topical Spironolactone work?

Spironolactone blocks androgen receptors in the skin. Androgens can increase oil production, leading to clogged pores and breakouts. By targeting these receptors, spironolactone helps reduce oil, prevent acne formation, and improve overall skin clarity.

Who is it for?

Topical spironolactone can be used by both men and women with hormonal acne. It’s especially helpful for those who want a targeted treatment without the systemic effects of oral medications. It's also suitable for people with sensitive skin.

Does it affect hormones?
Unlike oral spironolactone, the topical version mostly works where it’s applied. It doesn’t significantly impact overall hormone levels, making it a safer choice for those who want acne relief without affecting the rest of the body.

Why choose Oana?

Accessible

No need to visit a doctor's office or pharmacy. Our physicians see you from the comfort of your home then mail your treatments directly to your door.

Clinically-backed

All of our treatments are doctor trusted, evidence based, and custom made for you in FDA regulated pharmacies.

Affordable

We leverage telemedicine and compounding pharmacy services to offer you affordable pricing.

FAQ

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